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Crohn’s disease

Crohn's disease

Crohn’s disease is a chronic inflammatory bowel disease associated with the onset of ulcerative changes in the alimentary canal. Crohn’s disease can affect any portion thereof, starting from the mouth and reaches the anus, often particularly striking the Ileum (part of the small intestine located generally in the lower right area of the abdomen). Usually occurs between the ages of 15 and 40 years.

The inflammatory process in Crohn’s disease affects both the surface and deeper-lying layers of the wall most of the small intestine, thereby forming ulcerative changes. In a particularly strong inflammatory thrusts of the disease it is possible to disrupt the integrity of the intestinal wall and to form a channel (fistula) between adjacent intestinal loops between the small intestine and the other, adjacent organs (e.g., bladder) or skin.

The cause for occurrence of the disease has not yet been known. It is assumed that at its base is a viral or bacterial infection that leads to dysfunction of the immune system continued to exist after eliminating the infectious agent.

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