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Vasculitis disease

Vasculitis disease

Vasculitis is the name for a whole group of relatively rare diseases that are characterized by inflammation of blood vessels. The totality of all blood vessels in the body to form the vascular system. Blood vessels are generally divided into arteries that deliver to tissues and organs of blood rich in oxygen and veins that carry back to the lungs impoverished oxygen blood from the tissues. The word vasculitis comes from the Latin vasculum (blood vessel) and the suffix ‘IT’ meaning inflammation. Vasculitis is synonymous with the term angiitis. When inflammation affects the arterial vessels, the condition is also called arteritis, and when they are affected veins – venulit.

Vasculitis disease causes inflammation and damage to the wall of each of the relevant blood vessels. Inflammation can be transient (acute) or be available for a long period of time (chronic). The inflammatory process can vary in severity. In cases expressed the damage to the blood vessel wall violates supply of organs with blood, which deprives them of oxygen and nutrients. This can cause serious damage to tissues and organs, especially when affected are vessels of vital organs like the brain, lungs, kidneys and others. Each of the diseases in the group of vasculitis characterized by features resulting from the type of affected blood vessels manner and severity of damage to the vessels, the type and number of organs involved and specific abnormal results from laboratory tests.

Any disease from the group of vasculitis has its own distinctive “image” setting of a defined set of symptoms (complaints). To fall vasculitis diseases such as Kawasaki disease, Behcet’s disease, polyarteritis nodosa, Wegener’s granulomatosis, Takayasu’s arteritis, syndrome Chardzh-Strauss, Giant cell arteritis (temporal arteritis) and purpura Henon-Shonlayn. As well as a separate individual diseases, vasculitis disease can accompany and to exist within a number of medical conditions such as chronic infections (chronic hepatitis B and chronic hepatitis C), prolonged intake of certain drugs and substances (amphetamines and kokakin), cancers (lymphoma , multiple myeloma, and the like.), and rheumatic diseases (such as rheumatoid arthritis, systemic lupus erythematosus, etc).

Still cause the development of most forms Vasculitis disease remains unclear. It is assumed that most of them are related to problems in the functioning of the immune system (natural “defense” system of the body, which includes a number of organs, tissues, cells and molecules interacting with each other in a complicated way). The most generally accepted theory is that the body’s own immune system attacks differently wall of the affected blood vessels. To this are charged a certain genetic predisposition (in some vasculitis observed heredity greater frequency in certain families, depending on the age and gender, etc.) and “unlocking” the autoimmune reaction under the action of external agents such as infections, some drugs, harmful substances in the environment and the like.

In almost all cases of Vasculitis disease are found in the immune system and signs of inflammation in the vascular wall. Diseases of the group of vasculitis are relatively rare and can affect people of any age, gender, racial and social backgrounds. In particular diseases from the group observed a predominance of male or female, certain age and racial characteristics.

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